Clinical analysis of predictors of cervical lymph node metastases in unilateral multifocal papillary thyroid microcarcinoma
Objective To investigate the predictors of cervical lymph node metastases(LNM)in unilateral multifocal papillary thyroid microcarcinoma(PTMC).Methods The clinical data of 458 cases of unilateral multifocal PTMC from January 2010 to January 2020 from the Second Affiliated Hospital of Harbin Medical University were retrospectively analyzed.The risk factors for LNM in the central and lat-eral regions were analyzed by univariate and multivariate logistic regression analysis.Results Univariate analysis showed that total tumor diameter,extraglandular invasion,and Hashimoto's thyroiditis were closely related to central LNM(all P<0.05).Maximum tumor diameter,total tumor diameter,and central LNM were related to lateral LNM(all P<0.01).Multivariate analysis indicated that Hashimoto's thyroid-itis was an independent risk factor for central LNM(P<0.01),while total tumor diameter and central LNM were independent risk factors for lateral LNM(both P<0.01).Conclusions In unilateral multifocal PTMC,Hashimoto's thyroiditis is an independent risk factor for central LNM,while total tumor diameter and central LNM are independent risk factors for lateral LNM.