Clinical trials in medical treatent of lung cancer:a ten-year review and current landscape
Lung cancer remains the leading cause of cancer-related death,posing a serious threat to human health.Over the past decade,with the advent of the era of precision medicine,the landscape of lung cancer treatment has dramatically changed.A series of clinical trials related to perioperative immunotherapy or targeted therapy help to cure early-stage non-small-cell lung cancer(NSCLC).The application of immunotherapy and targeted therapy provides opportunities for patients with advanced NSCLC to achieve long-term survival.Addition-ally,a variety of new drugs,such as antibody-drug conjugates(ADCs),immune bispecific antibodies,and tumor vaccines,are expected to enhance the anti-tumor effectiveness.This article reviews important clinical trials in the field of lung cancer medical treatment over the past decade and discusses future directions based on the current treatment landscape.