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卵巢癌初始治疗和复发治疗的现状

Current status of primary treatment and recurrent treatment for ovarian cancer

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由于缺乏有效的早期筛查和诊断方法,绝大多数卵巢癌确诊时已为晚期,治疗难度大,易复发,预后差,死亡率居妇科恶性肿瘤之首.早期卵巢癌初始治疗以全面分期手术为主,部分患者需要辅助化疗;晚期卵巢癌初始治疗包括肿瘤细胞减灭术、辅助化疗和维持治疗.复发性卵巢癌治疗方法有限,可鼓励患者积极参加药物临床试验,根据铂敏感和铂耐药复发类型制定不同的治疗方案.本文分别针对卵巢癌的初始治疗和复发治疗现状作一述评,以期为卵巢癌的临床治疗提供参考.
The majority of ovarian cancer is diagnosed at an advanced stage,due to the lack of methods for early screening and diagno-sis.Ovarian cancer is characterized by difficult treatment,easy recurrence and poor prognosis,and the mortality rate ranks the first among gynecological malignant tumors.The primary treatment of early-stage ovarian cancer is mainly comprehensive staging surgery,and some patients require adjuvant chemotherapy.Primary treatment for advanced ovarian cancer includes cytoreductive surgery,adjuvant chemo-therapy,and maintenance therapy.Treatment options for recurrent ovarian cancer are limited,and patients are encouraged to actively par-ticipate in clinical trials.Patients can choose different treatment regimens according to the type of platinum-sensitive ovarian cancer and platinum-resistant ovarian cancer.This article reviews the current status of primary therapy and recurrent treatment for ovarian cancer,in order to provide reference for clinical practice.

epithelial ovarian cancerprimary therapyneoadjuvant chemotherapymaintenance therapyplatinum-sensitive ovarian cancerplatinum-resistant ovarian cancer

刘亚娜、郭瑞霞

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郑州大学第一附属医院妇科,河南省妇科恶性肿瘤防治医学重点实验室,河南省妇科肿瘤生育力保护工程中心,河南 郑州 450052

上皮性卵巢癌 初始治疗 新辅助化疗 维持治疗 铂敏感复发性卵巢癌 铂耐药复发性卵巢癌

2024

实用肿瘤杂志
浙江大学

实用肿瘤杂志

CSTPCD
影响因子:1.034
ISSN:1001-1692
年,卷(期):2024.39(5)