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卵巢癌初始治疗和复发治疗的现状

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由于缺乏有效的早期筛查和诊断方法,绝大多数卵巢癌确诊时已为晚期,治疗难度大,易复发,预后差,死亡率居妇科恶性肿瘤之首.早期卵巢癌初始治疗以全面分期手术为主,部分患者需要辅助化疗;晚期卵巢癌初始治疗包括肿瘤细胞减灭术、辅助化疗和维持治疗.复发性卵巢癌治疗方法有限,可鼓励患者积极参加药物临床试验,根据铂敏感和铂耐药复发类型制定不同的治疗方案.本文分别针对卵巢癌的初始治疗和复发治疗现状作一述评,以期为卵巢癌的临床治疗提供参考.
Current status of primary treatment and recurrent treatment for ovarian cancer
The majority of ovarian cancer is diagnosed at an advanced stage,due to the lack of methods for early screening and diagno-sis.Ovarian cancer is characterized by difficult treatment,easy recurrence and poor prognosis,and the mortality rate ranks the first among gynecological malignant tumors.The primary treatment of early-stage ovarian cancer is mainly comprehensive staging surgery,and some patients require adjuvant chemotherapy.Primary treatment for advanced ovarian cancer includes cytoreductive surgery,adjuvant chemo-therapy,and maintenance therapy.Treatment options for recurrent ovarian cancer are limited,and patients are encouraged to actively par-ticipate in clinical trials.Patients can choose different treatment regimens according to the type of platinum-sensitive ovarian cancer and platinum-resistant ovarian cancer.This article reviews the current status of primary therapy and recurrent treatment for ovarian cancer,in order to provide reference for clinical practice.

epithelial ovarian cancerprimary therapyneoadjuvant chemotherapymaintenance therapyplatinum-sensitive ovarian cancerplatinum-resistant ovarian cancer

刘亚娜、郭瑞霞

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郑州大学第一附属医院妇科,河南省妇科恶性肿瘤防治医学重点实验室,河南省妇科肿瘤生育力保护工程中心,河南 郑州 450052

上皮性卵巢癌 初始治疗 新辅助化疗 维持治疗 铂敏感复发性卵巢癌 铂耐药复发性卵巢癌

2024

实用肿瘤杂志
浙江大学

实用肿瘤杂志

CSTPCD
影响因子:1.034
ISSN:1001-1692
年,卷(期):2024.39(5)