Survival prognostic analysis of decompression and separation surgery for thoracolumbar metastases
Objective To explore the therapeutic efficacy and prognostic factors of decompression and separation surgery for thoracolum-bar spinal metastases.Methods The clinical and survival data of patients with thoracolumbar spinal metastases who were operated(n=50)and not operated(n=21)at our hospital from January 2012 to December 2019 were retrospectively analysed.Univariate and multivariate analysis of the survival of the patients treated with surgery were done by log-rank test and Cox regression analysis.Results The survival of the patients with surgery was significantly better than that of the patients without surgery[(19.67±2.66)months vs(13.38±1.40)months,P=0.039].Multivariate analysis showed that postoperative radiotherapy,combined visceral metastasis,Eastern Cooperative Oncology Group(ECOG)score and the interval of spinal metastasis were independent prognostic factors affecting the survival prognosis of patients with thoracolumbar spine metastases undergoing decompression and separation surgery(all P＜0.05).Conclusions The prognosis is not optimistic for patients with spinal metastases,and decompression and separation surgery can improve the prognosis.Postoperative radio-therapy,combined visceral metastasis,ECOG score and the interval of spinal metastasis are important prognostic factors.
spinal metastasisdecompression and separation surgeryradiotherapy
万方数据
维普
