摘要
恶性肿瘤是全球范围内威胁人类生命健康的重大公共卫生问题.早期、精确诊断是精准医学时代提高肿瘤治愈率和改善预后的关键.光学、X线、CT、MRI、超声和核医学等不同影像模态可从微观-介观-宏观水平表征肿瘤功能、代谢和解剖等信息变化,在肿瘤早期检测、诊断分期、疗效监测和预后评估中具有不可或缺的地位.本文阐述了不同影像方法在肿瘤诊疗中的临床应用进展,并探讨了肿瘤影像学在设备发展、影像探针/对比剂研发和临床转化等方面面临的挑战.
Abstract
Cancer represent a significant global public health concern,posing a substantial threat to human life and health.The enhance-ment of cancer survival rates and prognostic outcomes hinges on the early and precise diagnosis,particularly in the contemporary epoch of precision medicine.Various imaging modalities,such as optical imaging,X-ray,CT,MRI,ultrasound,and nuclear medicine,possess the capability to delineate alterations in tumor function,metabolism,and anatomy across microscopic,mesoscopic,and macroscopic scales.These modalities occupy a crucial role in the initial detection,diagnostic staging,monitoring of treatment,and prognostic evaluation of tu-mors.Despite their significance,numerous challenges persist in the realms of equipment advancement,the research and development of imaging probes/contrast agents,and clinical translation.
国家科技期刊平台
NSTL
万方数据