Analysis of clinical features and risk factors of liver injury patients caused by bee sting
Objective To investigate the clinical features and risk factors of liver injury caused by bee sting.Methods A retro-spective study was conducted,and 182 patients with bee stings who visited to the surgery department of Debao County People's Hospital from January 2017 to December 2021 were selected as the study subjects.The patients with alanine aminotransferase(ALT)≥80 U/L and/or totalbilirubin(TBIL)≥34.2 μmol/L were dividedinto liver injury group(26 patients),and the other patients were divided into non-liver injury group(156 patients).The laboratory results of the two groups were compared,including RBC,WBC,NEUT,NEUT(%),LYM,LYM(%),NRL,HB,PLT,MPV,prothrombin time(PT),activated partial thromboplastin time(APTT),TT,FIB,TBIL,ALT,aspartate aminotransferase(AST),CYSC,UREA,CREA,uric acid(UA)and the risk factors of liver injury were analyzed.Results(1)The incidence of liver injury in female patients was 13.16%(10/76),and that in male patients was 15.09%(16/106),and the difference was not statistically significant(P>0.05).(2)There were significant differences in ALT,TBIL,AST,UA,PT and APTT between the liver injury group and the non-liver injury group(P<0.05).(3)Logistic regression model analysis showed that AST(OR =1.011,95%CI:1.006~1.017,P =0.000)and PT(OR =1.688,95%CI:1.261~2.260,P =0.000)were independent risk factors for liver injury after bee sting.Conclusion After bee sting,it is necessary to monitor the AST and PT inde-xes of patients in time and intervene as early as possible to prevent liver injury.