Predictive value of albumin and prothrombin time ratio for prognosis of hepato-cellular carcinoma surgery
Objective To investigate the prognostic value of albumin and prothrombin time ratio(APT)in hepatocellular carcino-ma patients before hepatectomy.Methods 272 patients with hepatocellular carcinoma confirmed by clinical pathology were enrolled in the First Affiliated Hospital of Guangxi Medical University from January 2014 to December 2020.The ROC curve was established to determine the optimal cut-off value,and the patients were divided into high and low APT groups.COX analysis was used to screen the predictive factors for postoperative prognosis of patients with hepatocellular carcinoma,and the K-M curve was used to analyze the effect of APT on the prognosis of patients with hepatocellular carcinoma.Results The optimal cut-off value was 2.981.According to the optimal cut-off value,the APT was divided into high and low groups,with an area under the curve of 0.751(P<0.05).There was no significant correlation between total bilirubin,prothrombin time(PT),and AFP with the high and low APT groups(P>0.05).In addi-tion,APT was positively correlated with the prognosis of patients with hepatocellular carcinoma(P<0.05);in COX regression analy-sis,total bilirubin,AFP,and liver cirrhosis were not related to the prognosis of patients with hepatocellular carcinoma,but high and low APT were related to the prognosis of patients with hepatocellular carcinoma(Exp(B)=4.32,95%CI 1.824-10.27,P =0.001).Conclusion APT is an effective predictor of the prognosis of patients with hepatocellular carcinoma after surgery.
Hepatocellular carcinomaAlbumin and prothrombin time ratioPrognosisPrognostic factors
NETL
NSTL
万方数据
维普
