Previous studies have demonstrated that Follicular helper T cells are a special subgroup of CD4+T cells,which play an important role in promoting and regulating humoral response.However,there is still a need to fully elucidate how dendritic cells induce distinct Follicular helper T cells differentiation processes and their specific role in this induction.Therefore,this paper aims to compre-hensively review the roles of different subsets of dendritic cells in Follicular helper T cells differentiation.It concludes that continuous antigen presentation plays a crucial role in Follicular helper T cells differentiation while also highlighting the regulatory influence of OX40 signals downstream from CD28 and CD40L.thus,this paper seeks to enhance our understanding of the dendritic cells-Follicular helper T cellsaxis.
维普
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