复方丹参片联合脾切除治疗重型αβ地中海贫血1例
A case of Compound Danshen Tablets combined with splenectomy in the treat-ment of severe αβ thalassemia
林忠生 1黄国林 1潘振南 1莫丹丽 2陈相武3
作者信息
- 1. 广西壮族自治区岑溪市中医医院外科,广西岑溪 543200
- 2. 广西壮族自治区岑溪市中医医院儿科,广西岑溪 543200
- 3. 广西壮族自治区岑溪市中医医院检验科,广西岑溪 543200
- 折叠
摘要
报道1 例重型αβ-地中海贫血(地贫):α-地贫 1 基因杂合子(--SEA/αα)复合β-基因突变TATAboxnt-28(HBB:c,-78A→G)/β-基因突变CD 41～42(HBB:c,124～127 delTTCT)地贫双重杂合子患者.患者自幼贫血,随着年龄增长,症状逐年加重,需要输血维持,16 岁时贫血明显加重,巨脾症,脾功能亢进,住院进行完整性脾切除治疗.术后,给予复方丹参片以及叶酸、维生素B12、维生素E治疗,观察分析患者的临床征象、血液学指标中的红细胞、血红蛋白和免疫球蛋白.
Abstract
A case of severe alphaβthalassemia:heterozygote(--SEA/αα)complex β gene mutation TATAboxnt-28(HBB:c,-78A→G)/β-gene mutation CD41-42(HBB:c,124-127 delTTCT)thalassemia double heterozygote patients.Anemia since child-hood,with the growth of age,the symptoms of aggravated year by year,the need for blood transfusion maintenance,anemia at 16 years old significantly aggravated,giant spleen disease,hypersplenism,hospitalization for complete splenectomy treatment.After operation,the patients were treated with Compound Danshen Tablets and Folic acid,Vitamin B12 and Vitamin E.The clinical signs and hematological indicators of red blood cells,hemoglobin and immunoglobulin were observed and analyzed.
关键词
重型αβ地中海贫血/脾切除/复方丹参片Key words
Severe αβthalassemia/Splenectomy/Compound Danshen Tablet引用本文复制引用
出版年
2024
NETL
NSTL
万方数据