Progress in treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis by antibody-clearance blood purification technology
Anti-neutrophil cytoplasmic antibody-associated vasculitis(AAV)is a multisystem autoimmune disease with a high mortality and risk of progresses to end-stage kidney disease(ESKD).In addition to glucocorticoids and immunosuppressants,extracorporeal blood purification techniques have become essential adjuncts for the treatment of AAV,including plasma exchange,double-filtration plasmapheresis and immunoadsorption.In this study,the progress of antibody scavenging blood purification technology in the treatment of AAV and the changes of guidelines were systematically reviewed,so as to provide a reference for clinical treatment.
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