Secondary oxalate nephropathy after Whipple surgery
A 67-year-old male,presented with serum creatinine increased gradually accompanied with few proteinuria.The patient underwent Whipple surgery for pancreatic tumor 3 years ago and took Chinese herbal tea in recent months.Renal biopsy revealed interstitial and tubular lesions(acute on chronic),a large amount of crystal deposited in renal tubular lumen which exhibit colorful refraction under polarized light,ultimately diagnosed as oxalate nephropathy due to secondary hyperoxaluria.The renal function improved after 3 months of treatment with a low oxalate diet,plenty of drinking water,vitamin B6 and cholestastyramine.