COVID-19 infection induced anti-glomerular basement membrane nephritis with immune thrombocytopenia
This case reports one 34-year-old female patient who was admitted to the hospital with"nausea and vomiting for more than a month,gross hematuria with elevated serum creatinine for more than 20 days".The patient was diagnosed with COVID-19 infection and gastroenteritis in the local hospital prior to admission.Subsequently,the patient developed gross hematuria,decreased urine output with anemia,thrombocytopenia,progressive elevation of serum creatinine requiring renal replacement therapy,positive anti-glomerular basement membrane(GBM)antibody,and positive platelet-specific antibodies.Renal biopsy was anti-GBM nephritis.After being given anti-infective drugs,glucocorticoids,rituximab,cyclophosphamide and protein A immunoadsorption therapy,the patient's condition improved and she withdrew from dialysis.
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