Atypical anti-glomerular basement membrane disease after renal transplantation of Alport syndrome patient
A 19-year-old male presented with repeated increases of blood creatinine and urine protein six years after renal transplantation due to Alport syndrome and CKD stage 5D.Renal biopsy revealed mesangial proliferative glomerulonephritis,and linear deposition of IgG along glomerular basement membrane(GBM),and electron dense deposits in mesangial region on electron microscopy.The final diagnosis was allograft post-transplant anti-GBM nephritis,along with mixed rejection and immune complex nephritis.
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