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女性生殖道微生物组学在生殖医学中的研究进展

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女性生殖道是动态变化的微生态体系,存在着多种正常的微生物群落.生殖道微生物组是人体重要的微生态体系之一,与宿主、环境之间构成了相互制约、相互协调的微生态平衡,在维护女性生殖道健康中起到关键作用.临床上通过检测与评价健康或疾病状态下的生殖道微生态状况,可以及时发现生殖道疾病的危险因素,为不孕症的治疗提供指导与帮助.本文主要对近年来女性生殖道微生物组学的研究进展,特别是与生殖医学相关的进展加以综述,并展望生殖医学领域微生物组学未来的研究方向.
Research progress of reproductive tract microbiome in female reproductive medicine
Female reproductive tract is a dynamic microecological system with a variety of microbial communities.Female reproductive tract microbiology is one of the important microecosystems,which constitute a microecological balance of mutual restriction and coordination with host and environment and plays a key role in maintaining female reproductive tract health.By detecting and evaluating the microbiome of reproductive tract clinically,the risk factors of reproductive tract diseases can be found in time,providing guidance and help for the treatment of infertility.This paper mainly reviews the research progress of female reproductive microbiology in recent years,especially related to reproductive medicine,and looks forward to the future research direction of microbiology in the field of reproductive medicine.

Reproductive tract microbiomeReproductive medicine16S rRNA sequencing

杨璞玉、马彩虹

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100191 北京大学第三医院生殖医学中心

生殖道微生物组学 生殖医学 16S rRNA测序

北京大学第三医院临床重点项目

BYSY2015002

2018

中华生殖与避孕杂志
上海计划生育科学研究所

中华生殖与避孕杂志

CSTPCDCSCD北大核心
影响因子:0.989
ISSN:2096-2916
年,卷(期):2018.38(11)
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