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高强度聚焦超声消融治疗子宫腺肌病的研究进展

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子宫腺肌病(adenomyosis,ADS)是育龄期妇女常见的良性疾病,主要症状为痛经、月经量增多、子宫增大和不孕等.近年来随着ADS确诊患者的年轻化及生育政策的调整,保留生育功能的治疗方法逐渐受到重视.高强度聚焦超声(high-intensity focused ultrasound,HIFU)消融以其非侵入性、高准确性和可重复性等特点,较好地保留了子宫结构与功能的完整性,在保留生育功能的ADS治疗中展现出优势.HIFU消融治疗明显改善ADS患者的临床疗效以及妊娠结局,提高HIFU消融治疗ADS病灶的消融率更有益于上述结果.此外,HIFU消融相较其他微创治疗在保护生育力方面也具有一定优势.本文围绕HIFU消融治疗ADS保留生育功能的临床应用和研究总结作一综述.
Advances of high-intensity focused ultrasound ablation for the treatment of adenomyosis
Adenomyosis(ADS)is a common benign disease in women of childbearing age.The main symptoms are dysmenorrhea,increased menstrual volume,uterine enlargement and infertility.In recent years,with the younger age of ADS patients and the adjustment of fertility policy,the treatment of fertility preservation has gradually attracted attention.High-intensity focused ultrasound(HIFU)ablation has the characteristics of non-invasive,high accuracy and repeatability,which better preserves the integrity of uterine structure and function,and shows advantages in the treatment of ADS with fertility preservation.HIFU ablation significantly improves clinical outcomes as well as pregnancy outcomes in patients with ADS,and increasing the ablation rate of HIFU ablation for ADS lesions is more beneficial to these outcomes.In addition,HIFU ablation has some advantages in terms of fertility preservation compared with other minimally invasive treatments.This article reviewed the clinical application and research of HIFU ablation for ADS fertility preservation.

AdenomyosisPregnancy outcomesHigh-intensity focused ultrasound ablationReproductive function

汪沙、段华

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首都医科大学附属北京妇产医院 北京妇幼保健院妇科微创中心,北京 100006

子宫腺肌病 妊娠结局 高强度聚焦超声消融 生育功能

国家自然科学基金首都医科大学附属北京妇产医院中青年学科骨干培养专项

81571412FCYY201920

2024

中华生殖与避孕杂志
上海计划生育科学研究所

中华生殖与避孕杂志

CSTPCD北大核心
影响因子:0.989
ISSN:2096-2916
年,卷(期):2024.44(1)
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