Current status and research progress in the development of cryopreservation of human germ cells
Cryopreservation of human germ cells as a form of fertility preservation plays an important role in the development of assisted reproductive technology(ART),which has become one of the research hotspots in the field of reproductive medicine and is increasingly used in assisted reproductive practice.To improve the success rate of ART,cryopreservation techniques are constantly being improved in development,especially the selection of freezing strategies and the improvement and optimization of cryoprotectants.Cryopreservation is indicated for groups undergoing ART or for the freezing and preservation of oocytes,sperm and embryos due to reduced fertility caused by disease.It is also indicated for the cryopreservation of ovarian and testicular tissue for fertility preservation in cancer patients.However,the freezing effect of different freezing methods is not consistent for different germ cell types,and there is a lack of reasonable and valid criteria for evaluating the freezing effect of different germ cells.This paper reviews the current development and application of cryopreservation technology for human germ cells and discusses the future development of cryopreservation.
NETL
NSTL
万方数据
