肠道微生态与生殖障碍性疾病的相关研究进展
Relevant research progress of gut microbiota and reproductive disorders
赵敏 1庞艳莉1
作者信息
- 1. 北京大学第三医院妇产科生殖医学中心 女性生育力促进全国重点实验室 国家妇产疾病临床医学研究中心(北京大学第三医院) 辅助生殖教育部重点实验室(北京大学) 生殖内分泌与辅助生殖技术北京市重点实验室,北京 100191
- 折叠
摘要
当前育龄人群的生殖健康面临前所未有的挑战,不孕不育的患病率和不良妊娠结局的发生率逐年上升.肠道微生态作为人体的关键组成部分,在一系列正常生命活动的进行中发挥着重要作用.肠道微生态的紊乱已被证明参与多种疾病的进程,越来越多的研究表明,肠道微生态的紊乱与生殖障碍性疾病的发生发展有关.因此,本文将总结肠道微生态与女性生殖障碍性疾病的相关研究进展,为其防治提供新的策略,为提升育龄女性的生育力提供新的思路.
Abstract
At present,the reproductive health of childbearing age population is facing unprecedented challenges,with the incidence of infertility and adverse pregnancy outcomes increasing year by year.As a key component of human body,gut microbiota plays an important role in a series of normal life activities.The disturbance of gut microbiota has been proved to be involved in the process of many diseases,and more and more studies have shown that the disturbance of gut microbiota is also related to the occurrence and development of reproductive disorders.Therefore,this paper will summarize the relevant research progress of gut microbiota and female reproductive disorders,to provide new strategies for their prevention and treatment,and new ideas for improving the fertility of women of reproductive age.
关键词
生殖健康/多囊卵巢综合征/子宫内膜异位症/先兆子痫/复发性流产/早发性卵巢功能不全/肠道微生态Key words
Reproductive Health/Polycystic ovary syndrome/Endometriosis/Pre-eclampsia/Abortion,spontaneous/Primary ovarian insufficiency/Gut microbiota引用本文复制引用
基金项目
国家重点研发计划(2022YFC2702500)
国家自然科学基金(82171627)
国家自然科学基金(82022028)
&&(2019-I2M-5-001)
出版年
2024
NETL
NSTL
万方数据