常规体外受精(conventional in vitro fertilization,c-IVF)是利用优化后的精子与卵母细胞自然结合完成IVF的一类辅助生殖技术,主要应用于女性因素不孕、部分男性因素不育及不明原因不孕不育患者的助孕治疗.但目前尚缺乏c-IVF相关的操作标准或共识,尤其对于如何选择最佳授精方式以避免受精率低下或完全受精失败的发生,始终是困扰辅助生殖临床医生与胚胎实验室人员的难题.因此,由中国医师协会生殖医学专业委员会发起,并联合全国多家生殖医学中心共同编撰了本共识,旨在规范c-IVF的选择标准、精液优化处理及授精操作流程,为辅助生殖临床医生和胚胎实验室人员提供实用性参考,以期获得稳定且满意的辅助生殖助孕结局.
Chinese expert consensus on conventional in vitro fertilization(2024)
Conventional in vitro fertilization(c-IVF)is one of the most commonly used assisted reproductive technology(ART)approaches.In c-IVF,cumulus-intact oocytes are incubated with a defined range of spermatozoa,followed by a fertilization assessment a few hours later.c-IVF is primarily used for patients with female factor infertility,some cases with male factor sterility,and unexplained infertility.Given the absence of standardized operating protocols or consensus regarding c-IVF,the selection of an optimal insemination method poses challenges for ART clinicians and embryologists when dealing with special cases involving critical semen parameters.Therefore,this consensus was initiated through collaboration with the Chinese Association of Reproductive Medicine and collaboratively compiled by numerous reproductive medicine centers in China.The objective of this consensus is to establish standardized protocols for semen preparation and fertilization procedures in c-IVF while providing selection criteria for insemination methods.This consensus serves as a practical reference for ART clinicians and embryologists aiming to achieve consistent and satisfactory outcomes in ART.
Reproductive techniques,assistedConventional in vitro fertilizationSperm parametersSperm preparation methodsInsemination methodsConsensus
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