Progress in the application of different controlled ovarian stimulation protocols in IVF/ICSI treatment for POSEIDON patients
Patients with low-prognosis undergoing in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI)treatment are mainly manifested as poor ovarian response to exogenous gonadotropin stimulation and a lower clinical pregnancy rate than normal responders of the same age.In the past,Bologna criteria was used to define and diagnose those patients.In 2016,the Patient Oriented Strategies Encompassing Individualized Oocyte Number(POSEIDON)group proposed a new subdivision standard for low prognosis population in order to improve the homogeneity of them,which conceptually moved from poor response to poor prognosis and provided a classification basis for clinical treatment guidance and clinical counselling for POSEIDON patients.There are various controlled ovarian hyperstimulation protocols applied to POSEIDON groups,which have different effects on clinical application among different subgroups.This article will describe and summarize the progress of different ovulation induction regimens and adjuvant treatment strategies for patients with low-prognoses based on the POSEIDON criteria.
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