Effect of telocytes on pregnancy and its mechanism
The success of pregnancy relies on moderate trophoblast invasion,sufficient vascular remodeling and maternal-fetal tolerance.Recently,telocytes(TCs)have been widely reported as a novel type of interstitial cells.Functionally,TCs form a three-dimensional interstitial network by homocellular and heterocellular communication and are involved in tissue repair and regeneration,signal transduction,muscle contraction,secretion and immune regulation.One of the hotspots is the study of TCs in pregnancy establishment and pathological pregnancy.This paper reviews the role and possible mechanism of TCs on pregnancy,so as to provide more basis for exploring the role of TCs in embryo implantation and pregnancy maintenance.
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