饮用水中消毒副产物对成人生殖功能影响的研究进展
Research progress in the influence of disinfection by-products in drinking water on adult reproductive function
李娟 1邓陶然 1王怡 1廖宏梅 1李豫峰1
作者信息
- 1. 华中科技大学同济医学院附属同济医院生殖中心,武汉 430030
- 折叠
摘要
消毒副产物(disinfection by-products,DBPs)是饮用水消毒过程中消毒剂与水中的化学物质发生化学反应生成的化合物.目前已经鉴定的DBPs有700多种,其中含量最高的是三卤甲烷和卤代乙酸.DBPs的安全性问题已经引起了人们的广泛关注,目前研究已证实其具有细胞毒性、遗传毒性、致癌性、发育毒性.近年来DBPs对生殖功能的损害也逐渐引起人们的重视.本文从毒理学和流行病学两方面综述DBPs暴露对成人生殖功能影响的研究进展,并对其今后的研究方向进行相关讨论和展望.
Abstract
Disinfection by-products(DBPs)are compounds generated by chemical reactions between disinfectants and chemical substances in the water during the process of drinking water treatment.More than 700 kinds of DBPs have been identified,the most abundant components are trihalomethanes and haloacetic acids.The safety of DBPs has attracted widespread attention.At present,studies have confirmed that DBPs have cytotoxicity,genotoxicity,carcinogenicity and developmental toxicity.In recent years,the damage of DBPs to reproductive function has been an increasing concern.This article reviewed the research progress on the effects of DBPs exposure on adult reproductive function based on toxicological and epidemiological studies,and discussed the future research direction.
关键词
饮用水/水污染,化学性/生殖/毒理学/流行病学Key words
Drinking water/Water pollution,chemical/Reproduction/Toxicology/Epidemiology引用本文复制引用
基金项目
国家自然科学基金面上项目(81771654)
出版年
2024
NETL
NSTL
万方数据