葡萄糖转运蛋白对子宫内膜蜕膜化影响的研究进展
Research progress on the role of glucose transporters in regulating decidualization
高娜 1窦真 1赵晓丽 1王宝娟 1夏天1
作者信息
- 1. 天津中医药大学第一附属医院生殖医学科 国家中医针灸临床医学研究中心,天津 300381
- 折叠
摘要
葡萄糖转运蛋白(glucose transporters,GLUTs)在子宫内膜中广泛表达,介导葡萄糖摄取,调控子宫内膜基质细胞的能量代谢及蜕膜免疫代谢等过程,并与蜕膜化过程中重要的信号通路相互作用,影响胚胎植入.本文将对蜕膜化过程中GLUTs的表达及其作用机制作一综述,以期为不孕症及妊娠相关疾病的防治提供理论依据.
Abstract
Glucose transporters(GLUTs)are widely expressed in the endometrium,mediate glucose uptake,and regulate energy metabolism of endometrial stromal cells,as well as decidual immune metabolism and other related processes.GLUTs also interact with important signaling pathways during decidualization,affecting embryo implantation.In this paper,the aspects of GLUTs expression and mechanism during decidualization are reviewed in order to provide a theoretical basis for the prevention and treatment of infertility and pregnancy-related diseases.
关键词
葡萄糖转运蛋白/子宫内膜基质细胞/蜕膜化/胚胎植入Key words
Glucose transporter/Endometrial stromal cells/Decidualization/Embryo implantation引用本文复制引用
出版年
2024
NETL
NSTL
万方数据