维生素D调控子宫内膜异位症免疫学发病机制的研究进展
Research progress on the immunological pathogenesis of endometriosis regulated by vitamin D
廖琪 1徐芳 2冯晓玲 2匡洪影 2张晴 3孙淼2
作者信息
- 1. 黑龙江中医药大学研究生院,哈尔滨 150040
- 2. 黑龙江中医药大学附属第一医院妇科二科,哈尔滨 150040
- 3. 西安市中医医院妇科,西安 710021
- 折叠
摘要
维生素D作为一种重要的免疫调节素,通过与免疫细胞的维生素D受体结合,以影响其表达、增殖和凋亡等,从而发挥免疫调节作用,与慢性炎症性疾病、自身免疫性疾病等相关.近年研究显示,子宫内膜细胞也表达维生素D受体,并且子宫内膜异位症患者相关免疫因子表达水平与维生素D水平具有相关性.故本文就维生素D水平调控子宫内膜异位症免疫学发病机制的研究进展作一综述.
Abstract
As an important immunomodulator,vitamin D is involved in the expression,proliferation and apoptosis of immune cells through binding with the vitamin D receptor of immune cells,so as to play an immunomodulatory role,which is related to chronic inflammatory diseases and autoimmune diseases.Recent studies have found that endometrial cells also express vitamin D receptors,and the expression level of relevant immune factors in endometriosis patients are correlated with vitamin D levels.Therefore,this article will review the research progress on the regulation of vitamin D levels on the immunological pathogenesis of endometriosis.
关键词
维生素D/子宫内膜异位症/免疫学发病机制Key words
Vitamin D/Endometriosis/Immunological pathogenesis引用本文复制引用
基金项目
中国中西医结合妇产科专项研究基金普正制药专项(FCK-PZ-02)
中国中西医结合妇产科专项研究基金(FCK-ZSYTW-02)
出版年
2024
NETL
NSTL
万方数据