Research progress of chronic endometritis affecting embryo implantation
Chronic endometritis(CE)is an important pathological factor leading to infertility in women of childbearing age,and its characteristic manifestations are imbalanced immune-inflammatory homeostasis and abnormal microbial diversity.CE is an important factor leading to embryo implantation failure,which is closely related to the mechanism of chronic endometrial inflammation affecting follicle development,abnormal microflora mediating endometrial immune-metabolic microenvironment disorder,blocking mother-to-fetus interface signal communication,and reducing endometrial receptivity.In this paper,the characteristics of CE and its related mechanisms affecting embryo implantation were reviewed in order to provide therapeutic ideas for CE combined with embryo implantation failure.
Chronic endometritisEmbryo implantationEndometrial receptivityMaternal-fetal communication