Research progress on the unfolded protein response and female reproductive disorders
The unfolded protein response is triggered by the presence of unfolded or misfolded proteins in the endoplasmic reticulum and mitochondria,aiming to regulate and maintain cellular homeostasis under stress stimuli.Recent studies have shown that unfolded protein response plays a crucial role in the pathogenesis of female reproductive-related diseases.This article delves into the specific signaling pathways of unfolded protein response in the endoplasmic reticulum and mitochondria and summarizes its impact on the physiological functions and common diseases of the female reproduction,trying to provide novel potential therapeutic targets for the diagnosis and treatment of reproductive disorder related diseases.
Endoplasmic reticulumMitochondriaUnfolded protein responseReproductive system
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