Analysis of clinical characteristics of subclinical tuberculosis in infertile women
Objective To investigate the clinical characteristics of subclinical tuberculosis in infertile women.Methods A total of 2 129 infertile women screened for active tuberculosis were collected from January 2019 to January 2024 at Department of Gynecology and Pediatrics Tuberculosis in Xi'an Chest Hospital due to latent tuberculosis infection,and the clinical data of subclinical tuberculosis cases were retrospectively analyzed.Results The study identified 69 cases[3.2%(69/2 129)]of subclinical tuberculosis among these women.The age at diagnosis was(31.16±4.68)years,with an infertility duration of(3.81±2.58)years.About 94.2%(65/69)of these women had primary infertility.Some patients had adverse reproductive histories,including ectopic pregnancies,repeated assisted reproduction failures,missed miscarriages,and threatened miscarriages.Chest CT scans typically revealed fibrous cord-like consolidations,nodules and calcified nodules,pleural adhesions or minimal pleural effusions,calcification of hilar or mediastinal lymph nodes,and speckled combined with linear proliferative lesions.Hysteroscopic findings included chronic endometritis,endometrial polyps,and intrauterine adhesions.Hysterosalpingography frequently showed bilateral tubal occlusions,stenosis,and hydrosalpinx.Molecular biological assays indicated a lower bacillary load in most cases.Conclusion The clinical presentation of subclinical tuberculosis in infertile women is often atypical,with pulmonary lesions on chest CT being subtle and indicative of chronic conditions,which are frequently overlooked.
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