Objective To investigate the relationship between psychological status (depression & anxiety) and quality of life in stable chronic obstructive pulmonary disease (COPD) patients. Method A total of 66 clinically stable COPD patients was enrolled in this study. Score of St. George' s respiratory questionnaire (SGRQ) (assessing HRQOL) and Hamilton depression & anxiety scale (HAMD & HA-MA) were collected and correlated with pulmonary function and other clinical data. SPSS 17.0 statistical software was used to analyze the data. Result SGRQ scores increased (showing a worsening HRQOL) with increasing COPD severity. There were significant statistical differences in SGRQ total score, activity, impact and symptoms subscores between mild, moderate , severe and very severe COPD groups (P < 0.05). No statistical difference was found between mild, moderate and severe COPD groups as well as severe and very severe COPD groups. Also there were no significant difference in HAMD & HAMA scores across the stages of COPD and incidence of depression and anxiety. The SGRQ total scores, symptom and activity subscores were significantly worse in the patients with depression (P<0.05), and the SGRQ total scores, impact subscores and symptom subscores were significantly worse in the patients with anxiety (P <0.05). There were no significant differences in lung function ( FEV1/FVC, FEV1% ) in the pa-tients with or without depression and anxiety (P > 0. 05 ) . Conclusion Quality of life in stable COPD patients is associated with lung function and psychological status. In addition to routine intervention, it is also necessary to strengthen psychological treatment so as to improve quality of life in COPD patients.
chronic obstructive pulmonary diseasequality of lifeaffecting factors
NETL
NSTL
维普
万方数据
