Objective To study the association of dimethylformamide(DMF) exposure with chronic non-atrophic gastritis. Methods Firstly, a cross sectional survey was performed. 385 workers from 4 factories were examined, among them 28 cases of chronic non-atrophic gastritis were found as case group. All the objects were sorted according to gender and age. 1:4 match principle was used in the study that was 4 controls/1 case in each sub-group, therefore, 112 controls were selected. Additionally, Chi-square test and multivariable conditional logistic regression model were used for analysis and assessment of the association. Results (1) There was a similar prevalence of chronic non-atrophic gastritis in men and women; the prevalence was different with age(P<0.05). (2) The DMF exposure prevalence was significantly higher in case group. The major proportion of exposure duration were ≤5 years(P <0. 05) . (3) After adjusting the confounding factors such as smoking, drinking and other occupational exposure etc. the risk of chronic non-atrophic gastritis was obviously correlated to DMF exposure, especially the exposure less than 5 years (P <0. 05). Conclusion The results suggested that DMF exposure may increase the risk of chronic non-atrophic gastritis.
NETL
NSTL
维普
万方数据
