Monitoring the changes of serum sex hormone has an important role in adjusting gonadotropin dose in the process of ovarian stimulation.In early follicular phase,bFSH value can be used to predict ovarian response and pregnancy outcomes in IVF cycles.Increased estradiol (E2) levels can reflect the decreased ovarian reserve earlier than elevated FSH levels.For patients with reduced ovarian reservation (bFSH≥8 U/L),the value of FSH/LH in predicting the ovarian response is better than age and bFSH alone.There is a LH window during follicle development,so LH monitoring is important in the assessment of follicular development and adjustment of drug regimen timely.The elevated E2 levels can be used to predict ovarian response in advance in the early phase of ovarian stimulation.E2 level rapidly increasing indicates good ovarian function.On the contrary,E2 levels slowly raising or being stable,predicates poor ovarian response.However,the value of serum progesterone/E2 is more comprehensive than that of E2 or progesterone alone in late follicular phase.In conclusion,sex hormone assay in different stage of follicular development can help to select ovarian stimulation protocol and adjust gonadotropin dose,thus obtaining better clinical outcome.
国家科技期刊平台
NSTL
万方数据
维普
