Research progress on mechanism of reproductive disorders caused by microbial infections in chronic endometritis
Chronic endometritis(CE)is mainly a chronic inflammatory disease of the endometrium caused by pathogenic microorganisms in the uterine cavity,which is closely related to female reproductive disorders,but its specific mechanism is not yet clear.In recent years,studies have suggested that the main reason why chronic endometritis affects female reproductive outcomes is not only the presence of uterine microorganisms,but also the interaction between the microbial community and the endometrial microecology,which is related to uterine dysbiosis,metabolic changes,endometrial immune inflammation disorders,and abnormal gene expression.This paper reviews the research progress on the mechanism of microbiota in the occurrence and development of CE,as well as its impact on female reproductive health.It helps to provide scientific basis for optimizing treatment plans and improving reproductive prognosis in clinical practice.