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不同国家与地区辅助生殖临床数据特征的比较分析

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目的 通过比较我国与欧盟、美国、日本、澳大利亚与新西兰、拉丁美洲公开的2018年辅助生殖技术(ART)数据,了解不同国家与地区的ART助孕周期数、人群特点、ART助孕原因及助孕结局。方法 搜集我国与欧盟、美国、日本、澳大利亚与新西兰、拉丁美洲已公布的2018年ART数据,比较不同ART类型的治疗周期数、接受ART治疗的病因、女性年龄情况、临床妊娠率、活产率、多胎率及单胚胎移植占比等。结果 不同于其他国家与地区,我国ICSI周期数明显少于IVF周期数;我国和日本的冻融胚胎移植(FET)周期数明显多于新鲜周期。我国不孕不育夫妇进行ART治疗的主要原因是输卵管因素和男方因素,分别占47。90%和31。70%。我国接受ART治疗的女性中,大部分年龄小于<35岁,占ART治疗总人数的64%;而日本有51%接受ART治疗的女性年龄>40岁。相较于其他国家或地区,我国与美国的ART鲜胚移植周期与FET周期的临床妊娠率与活产率较高。我国的ART多胎率明显高于其他国家或地区,而单胚胎移植比例相对较低。结论 2018年我国不同类型的ART治疗周期、不孕女性年龄及不孕原因与其他国家或地区不同,虽然我国ART治疗成功率较高但多胎率也较高,需要进一步优化ART移植策略。
Comparison and analysis of clinical data characteristics of assisted reproduction between different countries and regions
Objective:To understand the differences of number of ART cycles,population characteristics,infertile causes,and ART outcomes in different countries and regions by comparing the publicly available 2018 ART data between China and European Union(EU),United States(US),Japan,Australia and New Zealand(ANZ),and Latin America(LA).Methods:The ART cycles,etiology of receiving ART treatment,female age,clinical pregnancy rate,live birth rate,multiple pregnancy rate,and single embryo transfer(SET)ratio were compared by collecting ART data from China,EU,US,Japan,ANZ and LA in 2018.Results:Unlike other countries and regions,China had remarkably less number of ICSI cycles than IVF cycles,and China and Japan had obviously more number of frozen embryo transfer(FET)cycles than fresh cycles.The main reasons for ART treatment for infertile couples in China were fallopian tube factor and male factor,accounting for 47.90%and 31.70%,respectively.Most women in China who received ART treatments were under 35 years old(accounting for 64%among infertile women),while 51%of women in Japan who received ART treatments were over 40 years old.Compared to other countries or regions,the clinical pregnancy rate and live birth rate both in fresh and FET cycles in China and the US were higher.The multiple pregnancy rate in China was obviously higher than that of other countries or regions,and the proportion of SET was relatively low.Conclusions:The types of ART treatment cycles,age of infertile women,and causes of infertility in China in 2018 are different from those in other countries or regions.Although the ART successful treatment rate in China is high but the multiple pregnancy rate is also high,and further optimization of embryo transfer strategies is needed.

Assisted reproductive technologyCountryRegionClinical pregnancy rateLive birth rateMultiple pregnancy rate

郑永杰、董杰

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空军军医大学基础医学院学员四大队,西安 710032

空军军医大学唐都医院生殖医学中心,西安 710038

辅助生殖技术 国家 地区 临床妊娠率 活产率 多胎率

国家自然科学基金

82101794

2024

生殖医学杂志
北京协和医院 国家人口计生委科学技术研究所

生殖医学杂志

CSTPCD
影响因子:1.24
ISSN:1004-3845
年,卷(期):2024.33(2)
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