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早发性卵巢功能不全中西医治疗研究现状

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早发性卵巢功能不全(POI)可导致女性不孕症,引起一系列类围绝经期症状,对年轻女性的身体和心理健康造成严重影响。其发病率逐年升高、发病年龄趋于年轻化,且目前尚无根治方法。POI的西医治疗方法有性激素补充治疗、脱氢表雄酮治疗、免疫抑制治疗、干细胞移植、基因治疗、辅助生殖技术等。中医治疗包括针灸治疗、中药膏方、中药汤剂等,其中中药汤剂益经汤较为经典,相关临床研究已证实其在改善POI患者的生殖功能上有较好的临床效果。本文就目前西医、中医对POI的治疗方法及各自优缺点进行综述,为POI的临床治疗提供更多参考。
Current research status on the treatment of premature ovarian insufficiency with traditional Chinese and western medicine
Premature ovarian insufficiency(POI)can lead to infertility in women,causing a series of perimenopausal symptoms,and is a dual physical and psychological blow to young women.Its incidence rate is increasing year by year,the age of onset tends to be younger,and there is no radical cure at present.Currently,Western medicine treatment includes sex hormone supplementation therapy,dehydroepiandrosterone therapy,immunosuppressive therapy,stem cell transplantation,gene therapy,assisted reproductive technology,and so on.Traditional Chinese medicine treatment includes acupuncture and moxibustion treatment,herbal ointment,herbal decoction,etc.The traditional Chinese medicine decoction Yijingtang has a long history,and the clinical researches have suggested its real effects on improving the reproductive function of POI patients.This article reviews the current methods of POI treatment with Western and Traditional Chinese Medicine,as well as their respective advantages and disadvantages,in order to provide reference for clinical treatment of POI and provide theoretical basis for further research on the treatment of POI.

Premature ovarian insufficiencyReproductive functionTraditional Chinese medicine Yijingtang

徐娅琼、赵淑云、周桦、张沛宇、杨路、赵孝梅、罗希、梁超

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贵州医科大学临床医学院,贵阳 550004

贵州医科大学附属医院生殖中心,贵阳 550004

早发性卵巢功能不全 生殖功能 中药益经汤

贵州省科技计划项目贵州省科技厅基础研究项目贵州省卫生健康委科学技术基金

黔科合基础-ZK[2023]重点040黔科合基础[2020]1Y337gzwjkj2019-1-008

2024

生殖医学杂志
北京协和医院 国家人口计生委科学技术研究所

生殖医学杂志

CSTPCD
影响因子:1.24
ISSN:1004-3845
年,卷(期):2024.33(2)
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