Summary of mechanisms under telomere-nuclear attachment in meiosis of germ cells
Germ cells produce gametes through meiosis,and the telomere-nuclear envelop(NE)attachment is the prerequisite for this vital physiological process.The proteins interact with each other to ensure the telomere-NE attachment and facilitate proper chromosome pairing,synapsis and homologous recombination during meiosis prophase I.In this paper,we will summarize findings about structures and functions of telomere-NE attachment related proteins and their complex,including Shelterin complex,meiosis specific linker of the nucleoskeleton and cytoskeleton complex(LINC),inner membrane related TERB1-TERB2-MAJIN(TTM)complex,and the SPDYA-CDK2 complex.
国家科技期刊平台
NSTL
万方数据
维普
