首页|体表子宫肌电监测技术在控释地诺前列酮栓促宫颈成熟中的临床探索

体表子宫肌电监测技术在控释地诺前列酮栓促宫颈成熟中的临床探索

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目的 应用体表子宫肌电监测技术探讨控释地诺前列酮栓促宫颈成熟时子宫肌电活动及其与临床结局的关系。方法 选择2020年1月至2023年1月在广州市妇女儿童医疗中心促宫颈成熟的单胎、头位孕妇89例,观察放置控释地诺前列酮栓后子宫肌电活动情况,并比较放置控释地诺前列酮栓不同时间出现子宫肌电爆发波的孕妇间临床结局的差异。结果 (1)控释地诺前列酮栓放置后肌电爆发波出现时间与促宫颈成熟耗时、临产间隔、放置至分娩用时呈正相关(P<0。05);(2)放置控释地诺前列酮栓后,3 h内出现子宫肌电爆发波组孕妇肌电强度显著高于3 h后出现组(P<0。05),且具有更短促宫颈成熟耗时、临产间隔、放置至分娩用时,以及更高24 h内分娩率(P<0。05),两组间总产程时长、产后出血率比较无统计学差异(P>0。05)。结论 放置控释地诺前列酮栓较早出现子宫肌电活动的孕妇促宫颈成熟时间更短、24 h阴道分娩率更高,但需重视产后出血发生风险。
Clinical exploration of surface uterine electromyography in patients with dinoprostone suppositories for cervical ripening induction
Objective:To explore the relationship between uterine electromyographic activity and clinical outcomes with surface uterine electromyography(EMG)monitoring technology in the application of controlled release of dinoprostone suppositories(PGE2)for cervical ripening induction.Methods:Eighty-nine singleton and cephalic pregnant women who underwent cervical ripening induction with PGE2 in Guangzhou Women's &Children's Medical Center from January 2020 to January 2023 were recruited to observe the uterine EMG.The clinical outcomes of patients with different occurrence of EMG burst were compared.Results:There was a positive correlation between the occurrence time of EMG burst and the duration of cervical ripening induction,the interval from placement to the beginning of labor and the interval from placement to delivery respectively(P<0.05).After the treatment of PGE2,the EMG intensity of patients whose uterine EMG burst appeared within 3 h was significantly higher than that of patients whose uterine EMG burst appeared after 3 h,and the patients whose uterine EMG burst appeared within 3 h had shorter duration of cervical ripening induction,the interval from placement to the beginning of labor and the interval from placement to delivery as well as higher delivery rate within 24 h(P<0.05).There were no significant differences in the total length of labor and the postpartum hemorrhage rate between the patients with two different reactions to PGE2(P>0.05).Conclusions:Pregnant women with early burst of myoelectric activity after placement of PGE2 had a shorter duration of cervical ripening induction and a higher 24-hour vaginal delivery rate.Attention should be paid to the risk of postpartum hemorrhage.

Dinoprostone suppositoriesInduction of laborSurface uterine electromyography monitoring technologyCervical ripening induction

程丹玲、杨金英、周冰倩、潘秀玉、董婷婷、刘慧姝

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深圳市龙岗区妇幼保健院(汕头大学医学院龙岗妇幼临床学院),深圳 518000

广州医科大学广州市妇女儿童医疗中心,广州 510623

控释地诺前列酮栓 引产 体表子宫肌电监测技术 促宫颈成熟

广州市临床高新技术项目广州市科技局母胎医学研究重点实验室项目

2019GX0720210201040113

2024

生殖医学杂志
北京协和医院 国家人口计生委科学技术研究所

生殖医学杂志

CSTPCD
影响因子:1.24
ISSN:1004-3845
年,卷(期):2024.33(7)
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