Clinical exploration of surface uterine electromyography in patients with dinoprostone suppositories for cervical ripening induction
Objective:To explore the relationship between uterine electromyographic activity and clinical outcomes with surface uterine electromyography(EMG)monitoring technology in the application of controlled release of dinoprostone suppositories(PGE2)for cervical ripening induction.Methods:Eighty-nine singleton and cephalic pregnant women who underwent cervical ripening induction with PGE2 in Guangzhou Women's &Children's Medical Center from January 2020 to January 2023 were recruited to observe the uterine EMG.The clinical outcomes of patients with different occurrence of EMG burst were compared.Results:There was a positive correlation between the occurrence time of EMG burst and the duration of cervical ripening induction,the interval from placement to the beginning of labor and the interval from placement to delivery respectively(P<0.05).After the treatment of PGE2,the EMG intensity of patients whose uterine EMG burst appeared within 3 h was significantly higher than that of patients whose uterine EMG burst appeared after 3 h,and the patients whose uterine EMG burst appeared within 3 h had shorter duration of cervical ripening induction,the interval from placement to the beginning of labor and the interval from placement to delivery as well as higher delivery rate within 24 h(P<0.05).There were no significant differences in the total length of labor and the postpartum hemorrhage rate between the patients with two different reactions to PGE2(P>0.05).Conclusions:Pregnant women with early burst of myoelectric activity after placement of PGE2 had a shorter duration of cervical ripening induction and a higher 24-hour vaginal delivery rate.Attention should be paid to the risk of postpartum hemorrhage.
Dinoprostone suppositoriesInduction of laborSurface uterine electromyography monitoring technologyCervical ripening induction