首页|辅助生殖技术中薄型子宫内膜的研究进展

辅助生殖技术中薄型子宫内膜的研究进展

扫码查看
在辅助生殖技术助孕过程中,合适的子宫内膜厚度是胚胎成功植入和提高妊娠率的重要条件。过薄的子宫内膜会导致胚胎反复种植失败,并且与较低的种植率、持续妊娠率和活产率相关。近年来这方面的科学问题受到越来越多学者的关注,但关于如何治疗薄型子宫内膜仍是一个尚未解决的临床难题。薄型子宫内膜定义的最低临界值目前还存在争议,但大多数研究将卵泡晚期子宫内膜厚度小于7 mm定义为薄型子宫内膜。在IVF/ICSI助孕中常常会根据子宫内膜厚度选择是否进行胚胎移植,子宫内膜厚度对胚胎移植成功率具有重要影响。目前国内外对于薄型子宫内膜不孕患者的治疗还没有统一的方案,亦未得出有效的治疗方案。本文具体讨论了关于薄型子宫内膜的病因、发病机制及治疗方案的研究进展,希望为辅助生殖领域中子宫内膜过薄不孕症患者的临床治疗提供参考。
Research progress on thin endometrium in assisted reproductive technology
In the process of assisted reproductive technology,the appropriate endometrial thickness is the key to improving embryo implantation and pregnancy rate.Excessively thin endometrium leads to repeated implantation failure and is associated with lower rates of implantation,persistent pregnancy,and live birth.In recent years,this scientific issue has drawn more and more attention from scholars,but the treatment of thin endometrium is still an unresolved clinical problem.The minimum threshold for the definition of thin endometrium is well debated,but most studies defined endometrial thickness of less than 7 mm as thin endometrium.In IVF/ICSI infertility patients are often evaluated for embryo transfer based on the endometrial thickness,which has an important impact on the success rate of embryo transfer,and at present there is no uniform protocol for the treatment of infertile patients with thin endometrium domestic and abroad,and no effective strategy has been derived.This article aims to discuss the progress of research on the etiology,pathogenesis and the treatment strategy of thin endometrium,and to provide a reference for the clinical treatment of infertile patients with thin endometrium in assisted reproduction technology.

Thin endometriumPregnancy outcomeEndometrial thicknessAssisted reproductive technology

张威、孟庆霞

展开 >

南京医科大学附属苏州医院/苏州市立医院生殖与遗传中心,苏州 215002

薄型子宫内膜 妊娠结局 子宫内膜厚度 辅助生殖技术

苏州市临床重点病种资助项目

LCZX202109

2024

生殖医学杂志
北京协和医院 国家人口计生委科学技术研究所

生殖医学杂志

CSTPCD
影响因子:1.24
ISSN:1004-3845
年,卷(期):2024.33(7)
  • 41