The value of endometrial hemorheology combined with receptivity in evaluating IVF-ET pregnancy outcomes in patients with hydrosalpinx
Objective:To analyze the value of endometrial hemorheology combined with receptivity in evaluating pregnancy outcomes after IVF-ET in patients with hydrosalpinx infertility.Methods:A total of 168 patients with hydrosalpinx infertility admitted to Northwest Women's and Children's Hospital from June 2021 to July 2023 were selected as the study objects,and were divided into pregnant group(128 cases)and non-pregnant group(40 cases)according to their pregnancy conditions.Before treatment,the basic data of the two groups and the intimal hemorheology and receptivity indexes detected by B-ultrasound were compared,and the influencing factors of non-pregnancy in patients with hydrosalpinx infertility were analyzed by binary logistic step-up regression model,and the effectiveness of receiver operating characteristic(ROC)curve in predicting non-pregnancy in patients with hydrosalpinx infertility was drawn.Results:After assisted pregnancy treatment,the pregnancy rate of 168 patients was 76.19％(128/168).There were no significant differences in age,infertility years,body mass index(BMI)and basal antral follicle count(AFC)between pregnant group and non-pregnant group(P＞0.05).Blood flow index(VI)and blood perfusion index(FI)of the pregnant group were significantly higher than those of the non-pregnant group(P＜0.05),and endometrial thickness,spiral artery resistance index(RI)and spiral artery pulse index(PI)and the proportion of endometrial shape of type C of the pregnant group were significantly lower than those of the non-pregnant group(P＜0.05).Binary logistic regression analysis showed that endometrial shape of type C,PI and RI of spiral artery,VI and FI as well as endometrial thickness were the influential factors of non-pregnancy in patients with hydrosalpinx infertility(P＜0.05).According to ROC curve analysis,combined detection of PI and RI of spiral artery VI,FI,endometrial shape of type C and endometrial thickness had the highest sensitivity(92.50％)and specificity(92.19％)in predicting non-pregnancy in patients with hydrosalpinx infertility.The value of combined test in predicting non-pregnancy in patients with hydrosalpinx was higher(AUC=0.922,P＜0.05).Conclusions:Spiral artery PI,VI,FI,spiral artery RI,endometrial shape of type C,endometrial thickness and other indicators are of high value in predicting non-pregnancy in patients with hydrosalpinx infertility.Through combined analysis of these indicators,the fertility of patients can be evaluated more comprehensively.
万方数据
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