The progress on predictive factors of successful microdissection testicular sperm extraction
Non-obstructive azoospermia(NOA)results in the absence of sperm in the semen due to a disorder of spermatogenesis in the testes,but multiple or isolated spermatogonial foci may still be present in the testes.Men with NOA may also be able to produce their own biological offspring with the assistance of ICSI,as long as sufficient sperm can be obtained in the testes through sperm retrieval procedures.Unlike traditional testicular sperm retrieval,microdissection testicular sperm extraction(M-TESE)greatly improves sperm retrieval by using a surgical microscope to microscopically dissect the testicular tissue in search of spermatogonial foci.Although sperm retrieval by microdissection testicular sperm extraction is the best method for NOA patients,the positive rate is not high.At present,there is a lack of more accurate predictive indicators,so the qualitative and localization diagnosis of spermatogenic zone is of great significance.The article is to summarize the predictors of M-TESE outcomes and the prediction techniques that may have application value in the future,in order to provide reference for the clinical diagnosis and treatment of NOA.