Objective:To investigate the correlation between triglyceride glucose(TyG)index and triglyceride glucose body mass index(TyG-BMI)with hypertension.Methods:People over 35 years old who underwent physical examination in medical institutions in Nanjing were included in the study from January 2019 to 2022 December.According to the diagnostic standard of hypertension,the subjects were divided into hypertension group and hypertension normal group.General demographic characteristics,disease history,life habits and other information were collected,height,weight,blood pressure and biochemical indicators,blood glucose and other indicators were measured,and the differences in general conditions were compared with two groups.Pearson correlation analysis and Logistic regression were used to analyze the correlation of TyG,TyG-BMI with prevalence of hypertension,respectively.Results:A total of 917 people were included in this study,including 524 male and 393 female,with the average age of 57.13±14.07.Pearson correlation analysis showed that with the increasing of TyG and TyG-BMI levels,the levels of systolic blood pressure(SBP)and diastolic blood pressure(DBP)also increased.And the prevalence of hypertension also increased with the increase of TyG and TyG-BMI groups according to quartile,and the trend chi-square difference was statistically significant(χ2 =34.510,108.511,P<0.001).Further Logistic regression analysis showed that TyG and TyG-BMI were both independent risk factors for hypertension,and the risk of developing hypertension was positively associated with both TyG and TyG-BMI concentrations(OR =1.839,95%CI:1.254-2.695;OR = 1.021,95%CI:1.014-1.028).Grouped by quartile,the risk of hypertension in the TyG-BMI third quartile group was 2.366 times than that in the first quartile group(95%CI:1.189-4.708),and the risk of hypertension in the fourth quartile group of TyG-BMI was 5.780 times than that in the first quartile group(95%CI:2.855-11.699).ROC curve analysis results showed that the truncation value of TyG in predicting hypertension was 8.99,the area under the curve was 0.630,the sensitivity was 0.378,and the specificity was 0.850.The cutoff value of TyG-BMI for predicting hypertension was 216.56,the area under the curve was 0.710,the sensitivity was 0.592,and the specificity was 0.733.Conclusion:TyG and TyG-BMI are linearly positively correlated with blood pressure,and are independent risk factors for hypertension.TyG-BMI is more valuable than TyG in predicting the risk of hypertension.
hypertensiontriglyceride glucose indextriglyceride glucose body mass indexrisk factors
NETL
NSTL
维普
万方数据
