Objective:To evaluate the effect of different interventions on intensive care unit-acquired weakness by mesh Meta-analysis.Methods:Embase,PubMed,Web of Science,WanFang Data,CNKI and VIP databases were systematically searched from inception to May 2023.The reviewers independently selected studies,extracted data and evaluated the quality of studies.Stata 15.1 Software was used to perform the Meta-analysis.Results:A total of 29 articles were included,including 2 188 patients.The results of network Meta-analysis showed that in the best probability ranking of MRC score the best effect was Chinese medicine treatment+acupuncture treatment.In the best probability ranking of APACHE Ⅱ score,the best effect was traditional Chinese medicine treatment+acupuncture treatment.In the best probability ranking of MBI score,the best effect was rehabilitation training+external diaphragm pacing.In the best probability ranking of ICU stay,the best effect was early rehabilitation training.In the best probability ranking of mechanical ventilation time,the best effect was traditional Chinese medicine treatment+acupuncture treatment.In the best probability ranking of total hospital stay,early rehabilitation training had the best effect.The best probability ranking of IL-6 was early rehabilitation training.Conclusion:The current evidence showed that the 12 interventions are helpful for intensive care unit-acquired weakness,but Chinese medicine therapy+acupuncture therapy,early rehabilitation training,rehabilitation training+in vitro diaphragm pacing may be the best intervention,and more studies are needed to prove it in the future.
intensive care unitpatients with acquired weaknessclinical effectnetwork Meta-analysisrandomized controlled trial
NETL
NSTL
万方数据
