Objective:To investigate the effect of percutaneous vertebral body stent system in the treatment of osteoporotic vertebral compression fractures.Methods:We searched PubMed,the Cochrane Library,Embase,China National Knowledge Infrastructure,Wanfang database and VIP database for all the articles about the treatment of osteoporotic vertebral compression fracture using vertebral body stent system or percutaneous kyphoplasty from the establishment of databases to December 31st,2023.The outcome measures included Cobb Angle of fractured vertebrae,Beck Index of fractured vertebrae,Visual Analogue Scale(VAS),Oswestry Dysfunction Index(ODI),bone cement leakage rate,operative time,intraoperative blood loss and bone cement injection.RevMan 5.4 software was used for Meta-analysis.Results:9 studies including 662 subjects were included in the analysis.The results of Meta-analysis showed that the treatment of osteoporotic vertebral compression fractures with percutaneous vertebral body stent system was superior to percutaneous kyphoplasty in terms of Cobb Angle(MD=-2.47 degree,95％CI-3.75--1.19 degree,P=0.000 2),Beck Index(MD=0.18,95％CI 0.01-0.36,P=0.04)and bone cement leakage rate(MD=0.48,95％CI 0.28-0.81,P=0.006),but the former had longer operation time(MD=5.91 min,95％CI 0.24-11.58 min,P=0.04)and more bone cement(MD=1.45 mL,95％CI 0.30-2.60 mL,P=0.01).There were no significant differences in VAS score of pain(MD=-0.18,95％CI-0.40-0.04,P=0.12),ODI(MD=-0.58,95％CI-1.74-0.57,P=0.32)and intraoperative blood loss(MD=0.06 mL,95％CI-0.27-0.38 mL,P=0.73)between the two groups.Conclusion:The clinical efficacy of percutaneous vertebral body stent system in the treatment of osteoporotic vertebral compression fractures is comparable to that of percutaneous kyphoplasty,and it has more advantages in the correction of kyphotic deformity and the reduction of bone cement leakage.
osteoporotic vertebral compression fracturevertebral body stentpercutaneous kyphoplasty
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