首页|药物支架辅助的内镜下鼓室成形术Ⅰ型治疗慢性化脓性中耳炎的疗效分析

药物支架辅助的内镜下鼓室成形术Ⅰ型治疗慢性化脓性中耳炎的疗效分析

Analysis of the therapeutic effect of drug stent-assisted endoscopic tympanoplasty type Ⅰ in the treatment of chronic suppurative otitis media

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目的:探讨药物支架辅助的内镜下鼓室成形术Ⅰ型治疗慢性化脓性中耳炎的疗效.方法:选择2022年10月至2024年1月于我院治疗的124例单纯性慢性化脓性中耳炎患者为研究对象,随机分为实验组[64例(64耳)]和对照组[60例(60耳)].实验组给予药物支架辅助的内镜下鼓室成形术Ⅰ型,对照组给予传统内镜下鼓室成形术Ⅰ型.记录两组患者的出血量、手术时间、住院时间、干耳时间、疗效、术后不良反应,术前术后的听力、疼痛视觉模拟评分(VAS)、患耳外耳道横截面积、生活质量综合评定问卷-74(GQOL-74).结果:与对照组比较,实验组的手术时间显著延长(P<0.05),两组的出血量和住院时间差异无统计学意义(P>0.05).术前,两组的气道听阈、气骨导差、骨导听阈、VAS、患耳外耳道横截面积、生活质量评分差异无统计学意义(P>0.05).术后2周、4周,两组的气道听阈、气骨导差、骨导听阈、VAS均有不同程度地降低(P<0.05),与对照组比较,实验组的气道听阈、气骨导差、骨导听阈、VAS均显著降低(P<0.05);与对照组比较,实验组术后3个月的患耳外耳道横截面积和生活质量均显著增高,干耳时间显著减少(P<0.05).与对照组比较,实验组的总有效率显著增高(P<0.05).两组各1例术后出现轻度感染,其余患者均未出现显著的不良反应.结论:药物支架辅助的内镜下鼓室成形术Ⅰ型可用于治疗慢性化脓性中耳炎,可显著缩短干耳时间、改善听力、缓解疼痛、扩大患耳外耳道横截面积和改善生活质量.
Objective:To explore the therapeutic effect of drug stent-assisted endoscopic tympanoplasty type Ⅰ in the treatment of chronic suppurative otitis media.Methods:From October 2022 to January 2024,124 patients with simple chronic suppurative otitis media admitted to our hospital were collected and randomly divided into experimental group[64 cases(64 ears)]and control group[60 cases(60 ears)].The experimental group received drug stent-assisted endoscopic tympanoplasty type Ⅰ,while the control group received traditional endoscopic tympanoplasty type Ⅰ.The bleeding volume,surgical time,hospital stay,dry ear time,therapeutic effect,postoperative adverse reactions,preoperative and postoperative hearing,pain visual analog scale(VAS),cross-sectional area of the affected ear canal,generic quality of life inventory-74(GQOL-74)of the 2 groups were documented.Results:Compared with the control group,the surgical time of the experimental group was significantly increased(P<0.05).There was no statistically significant difference in bleeding volume and hospital stay between the 2 groups(P>0.05).Before surgery,the airway hearing threshold,air bone conduction difference,bone conduction hearing threshold,VAS,cross-sectional area of the affected ear canal and quality of life score had no differences between the 2 groups(P>0.05).At 2 and 4 weeks after surgery,the airway hearing threshold,air bone conduction difference,bone conduction hearing threshold,and VAS of the 2 groups were all reduced(P<0.05).Compared with the control group,bone conduction hearing threshold,the airway hearing threshold,air bone conduction difference,and VAS of the experimental group were significantly reduced(P<0.05).Compared with the control group,the cross-sectional area of the affected ear canal and quality of life score of the experimental group was significantly increased at 3 months after surgery,and the dry ear time was significantly reduced(P<0.05).Compared with the control group,the total effective rate of the experimenal group was significantly increased(P<0.05).1 patient in each group had mild infection after surgery,and the rest of the patients had mild infection.Conclusion:Drug stent-assisted endoscopic tympanoplasty type Ⅰ can be used to treat chronic suppurative otitis media,which can significantly shorten ear drying time,alleviate pain,improve hearing,increase cross-sectional area of the affected ear canal and improve quality of life.

drug stentendoscopechronic suppurative otitis mediatympanoplasty

陈白、李巍、姚仲镟、王浩、赵泽祺、肖朝球

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徐州医科大学第一临床医学院,江苏徐州 221004

徐州医科大学附属医院耳鼻咽喉头颈外科,江苏徐州 221004

药物支架 内镜 慢性化脓性中耳炎 鼓室成形术

2024

现代医学
东南大学

现代医学

CSTPCD
影响因子:0.703
ISSN:1671-7562
年,卷(期):2024.52(9)