Correlation of electrophysiological and ablation characteristics with the age and gender in children with paroxysmal supraventricular tachycardia treated with radiofrequency ablation
Objective:To investigate the correlation of electrophysiological and ablation characteristics and laboratory indexes with the age and gender in children with paroxysmal supraventricular tachycardia(PSVT)treated with radiofrequency ablation.Methods:The clinical data of 156 PSVT children treated with radiofrequency ablation in our hospital from January 2020 to December 2023 were retrospectively analyzed,and the correlation of electrophysiological and ablation characteristics and laboratory indexes with the age and gender was analyzed.Results:Among 156 cases of PSVT children,72(46.15％)had atrioventricular nodal reentrant tachycardia(AVNRT)and 84(53.85％)had atrioventricular reentrant tachycardia(AVRT).The proportion of AVNRT in male children was significantly higher than that in AVRT(P＜0.05).The proportion of AVRT in children aged 3-6 years was higher,and the proportion of AVNRT in children aged 7-14 years was higher(P＜0.05).The proportion of AVNRT in children aged 7-14 years was significantly higher than that in children aged 3-6 years(P＜0.05).The proportion of bidirectional bypass conduction in children aged 3-6 years was higher,and the proportion of occult bypass tracts in children aged 7-14 years was higher(P＜0.05).Before radiofrequency ablation,the B-type natriuretic peptide(BNP)in female children was significantly higher than that in males,and the creatine kinase-MB isoenzyme(CK-MB)was significantly lower than that in males(P＜0.05).The N-terminal prohormones of brain natriuretic peptide(NT-proBNP)in female children were higher than those in males at 12 h after treatment(P＜0.05),and the CK-MB and creatine kinase(CK)in all children were significantly higher at 12 h after treatment(P＜0.05),while the BNP,NT-proBNP,K+,Ca2+,Na+,platelet-to-lymphocyte ratio(PLR),systemic immuno-inflammatory index(SII)and red cell distribution width(RDW)were significantly lower(P＜0.05).Before radiofrequency ablation,the BNP increased significantly with age(P＜0.05),while the CK decreased significantly(P＜0.05),the NT-proBNP increased significantly with age at 12 h after surgery(P＜0.05),and the CK-MB and CK increased significantly at 12 h after treatment(P＜0.05).The K+,Ca2+,Na+,PLR,SII and RDW decreased significantly(P＜0.05),while the postoperative BNP and NT-proBNP of children aged 7-14 years were significantly reduced(P＜0.05).Conclusion:The age and gender of children are associated with different types of PSVT,and with the electrophysiological,ablation characteristics and several laboratory indicators of PSVT children.
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