Objective:To analyze the health status of middle-aged women in Shanghai and explore the impact of menopausal status on health.Methods:The physical examination data of 30％physical examination women aged 40 to 60 years from January to December 2021 were collected,and the subjects were divided into pre-menopause,perimenopause and postmenopause groups according to menopausal status.The differences in lifestyle,clinical indicators and prevalence of chronic diseases among middle-aged women under different menopausal status were compared.Logistic regression was used to analyze the correlation between menopausal status and common chronic diseases in women.Results:Totally 9 094 female health examination subjects aged 40 to 60 years were included in the study.Drinking,diet and exercise were different in different menopausal women(P＜0.05).The levels of body mass index,diastolic blood pressure,systolic blood pressure,triglyceride,cholesterol,low density lipoprotein,fasting blood glucose,uric acid,creatinine were different in different menopausal women(all P＜0.05).The prevalence of Helicobacter pylori infection,cervical diseases,breast nodules,and anemia decreased in perimenopause or postmenopause(all P＜0.05).Except for pulmonary nodules,the prevalence of other diseases increased in perimenopause or postmenopause(all P＜0.05).After adjusting for smoking,drinking,diet and exercise,postmenopause was risk factor for type 2 diabetes[OR=2.327,95％CI:(1.096,4.938)]in women aged 40 to 49 years(P＜0.05),perimenopause and postmenopause were risk factors for dyslipidemia[OR=1.574,95％CI:(1.279,1.937);OR=2.668,95％CI:(2.005,3.549)],hyperuricemia[OR=1.828,95％CI:(1.075,3.109);OR=3.751,95％CI:(2.207,6.375)]and fatty liver[OR=1.552,95％CI:(1.213,1.985);OR=1.540,95％CI:(1.110,2.136)](all P＜0.05);perimenopause and postmenopause were risk factors for type 2 diabetes[OR=2.656,95％CI:(1.397,5.053);OR=3.163,95％CI:(1.756,5.698)],dyslipidemia[OR=1.669,95％CI:(1.337,2.083);OR=1.799,95％CI:(1.496,2.164)],hyperuricemia[OR=2.326,95％CI:(1.379,3.924);OR=2.029,95％CI:(1.259,3.269)]and fatty liver[OR=1.907,95％CI:(1.488,2.445);OR=2.012,95％CI:(1.623,2.494)]in women aged 50 to 60 years(all P＜0.05).Conclusion:There are some differences in the health condition of women with different menopausal status;menopausal status are the risk factors of type 2 diabetes mellitus,dyslipidemia,hyperuricemia and fatty liver in middle-aged women;lifestyle intervention should be strengthened to improve the health status of middle-aged women.
维普
万方数据
