Objective:To explore effective clinical treatments for aplastic anemia-paroxysmal nocturnal hemoglobinuria(AA-PNH).Methods:Clinical data of two AA-PNH patients were reviewed retrospectively.Results:Two patients who underwent hematopoietic stem cell transplantation(HSCT)had no obvious GVHD during the course of the disease.Blood routine monitoring was performed after discharge,and the dependence on blood transfusion was reduced little by little.They are now able to discontinue blood transfusion and their hematopoietic function is gradually recovering.Conclusion:There are various clinical treatments for AA-PNH,but HSCT has superior to others after comparison.
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