Objective:This study introduces the fuzzy comprehensive evaluation method to more accurately evaluate the rational use of sterilization packaging materials in surgical item packaging,in order to improving the overall operational efficiency and service quality of disinfection supply center.Methods:Fuzzy comprehensive evaluation method was used to comprehensively evaluate various sterilization packaging materials,and the scores of different packaging materials used for three different weight of surgical instrument packages were calculated.Finally,the optimal packaging materials corresponding to the three categories of surgical instrument packages were optimized.The control group was the equipment package without unified packaging materials implemented in December 2022,and the experimental group was the equipment package with unified packaging materials implemented in June 2023,the qualification rate of goods packaging,operational convenience,and clinical departments satisfaction were compared between the two groups.Results:Hard containers showed the highest systematic score of 3.38 in surgical item category 1(5-7 kg)and were recommended as the preferred packaging material for this item category.For surgical item categories 2(3-5 kg)and 3(<3 kg),paper plastic packaging bags have achieved the highest system score due to their high efficiency and economic advantages,making them the preferred packaging material.After implementing the optimized packaging material management strategy,the qualification rate of goods packaging,operational convenience,and clinical departments satisfaction of the experimental group were significantly higher than those of the control group,and the difference was statistically significant(P<0.01).Conclusion:The fuzzy comprehensive evaluation method provides a scientific and reasonable decision-making basis for the selection of packaging materials for disinfection supply center,achieving a dual improvement in economic benefits and work efficiency.It is a quantifiable indicator of sterilization packaging efficiency that is worth promoting.