Retrospective Analysis of Clinical Characteristics and Neonatal Outcomes of Pregnant Women with SARS-COV-2 Infection

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外文摘要：This retrospective study aimed to investigate the clinical characteristics and neonatal outcomes of pregnant women with SARS-COV-2 in Wuhan Children's Hospital and further suggested a possible management strategy for infected pregnant women under epidemic situation.In this study,8 pregnant women with SARS-COV-2 who were admitted into Wuhan Children's Hospital,China from February 1,2020 to March 30,2020 and the clinical features,laboratory data,maternal and neonatal outcomes were analyzed.The mean age of the women at the time of admission was 30.6 years.The mean gestational age of the women was 37 weeks+4 days,and one woman presented with dichorionic diamniotic (DCDA) twin pregnancy.Except for one woman who was febrile,others had no typical clinical symptoms.For all pregnant women,the count of white blood cells and lymphocytes appeared normal,but 6 had a lower percentage of lymphocytes.C-reactive protein (CRP) levels were normal for all the women.One neonate was tested positive for the coronavirus IgG and IgM antibodies.The clinical symptoms of the pregnant women with SARS-COV-2 were mild,and the laboratory data showed similar characteristics to those of non-infected pregnant women.Since one neonate was tested positive for coronavirus,there is a possibility of vertical transmission of SARS-CoV-2.Prompt and efficient screening,triage,and isolation of pregnant women are effective management strategies to reduce nosocomial infection during the SARS-COV-2 epidemic.

外文关键词：

SARS-COV-2vertical transmissionpregnant womenneonatesclinical featuresmaternal and child outcomes

作者：

Yu CHEN、Xiang-li PANG、Wen-ping DING、Xiang-chi PENG、Jing YANG、Yan ZHOU

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作者单位：

Reproductive Medicine Center, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China

Reproductive Medical Center, Renmin Hospital of Wuhan University, Wuhan 430060, China

Department of Diagnostic Ultrasound, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China

Department of Obstetrics and Gynecology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital),Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China

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基金：

This project was supported by Wuhan Health Commission Fund,China

项目编号：

WX14A08

出版年：

2021

DOI：

10.1007/s11596-021-2347-9

当代医学科学(英文)

同济医科大学

当代医学科学(英文)

SCI

ISSN：2096-5230

年,卷(期)：2021.41(2)

参考文献量22