首页|Risk Factors of Enternal Nutrition Intolerance in Septic Patients:A Case-control Study

Risk Factors of Enternal Nutrition Intolerance in Septic Patients:A Case-control Study

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Objective:This study aimed to investigate the incidence of enteral nutrition intolerance(ENI)in patients with sepsis and explore potential risk factors.Methods:A case-control study was conducted in patients with sepsis who were receiving enteral nutrition(EN)at a tertiary hospital in China.The included patients were divided into the ENI group and the non-ENI group.Univariate and multivariate analyses were performed to identify the risk factors for ENI.Results:A total of 859 patients were included in the study.Among them,288(33.53%)patients experienced symptoms of ENI,including diarrhea,vomiting,bloating,and gastric retention.Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)score,thoracocentesis,and usage of cardiotonic drugs(namely,inotropes)were independent predictors of the ENI.Conclusion:The incidence of ENI is relatively high in patients with sepsis,especially in those who have higher APACHE Ⅱ scores,have undergone thoracocentesis,and have received inotropes.

sepsisenteral nutrition intoleranceinfluencing factor

Li-zhu WANG、Yan XIANG、Qian LI、Yi-rong ZHU、Jue FANG、Xiao-dan LU、Zhao-cai ZHANG

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Department of Nursing,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China

Department of Critical Care Medicine,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China

Key Laboratory of the Diagnosis and Treatment for Severe Trauma and Burn of Zhejiang Province,Hangzhou 310009,China

Zhejiang Province Clinical Research Center for Emergency and Critical Care Medicine,Hangzhou 310009,China

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National Key Research and Development Program of ChinaNational Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaZhejiang Provincial Natural Science Foundation of ChinaZhejiang University Horizontal Program

2021YFC25018008227218282072202LHDMD22H02001K-Horizontal 20202295

2024

当代医学科学(英文)
华中科技大学同济医学院

当代医学科学(英文)

影响因子:0.748
ISSN:2096-5230
年,卷(期):2024.44(2)
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