首页|Immunomodulation of Proton-activated G Protein-coupled Receptors in Inflammation
Immunomodulation of Proton-activated G Protein-coupled Receptors in Inflammation
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NETL
NSTL
万方数据
Proton-activated G protein-coupled receptors(GPCRs),initially discovered by Ludwig in 2003,are widely distributed in various tissues.These receptors have been found to modulate the immune system in several inflammatory diseases,including inflammatory bowel disease,atopic dermatitis,and asthma.Proton-activated GPCRs belong to the G protein-coupled receptor family and can detect alternations in extracellular pH.This detection triggers downstream signaling pathways within the cells,ultimately influencing the function of immune cells.In this review,we specifically focused on investigating the immune response of proton-activated GPCRs under inflammatory conditions.
proton-activated G protein-coupled receptorsinflammationimmunomodulationdisease
Min-shan LI、Xiang-hong WANG、Heng WANG
展开 >
Department of Otolaryngology-Head and Neck Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China
Institute of Allergy and Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China
Hubei Clinical Research Center for Nasal Inflammatory Diseases,Wuhan 430030,China
NETL
NSTL
万方数据
