Effect of Jianpi Shengxue Tablet on Iron Metabolism and Nutritional Status in Patients with Renal Anemia:A Prospective,Randomized,Open,Parallel Controlled and Multicenter Clinical Study

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外文摘要：Objective:This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods:A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results:After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P＜0.01),and the clinical symptom score and total iron binding capacity decreased(P＜0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P＜0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P＜0.01).Conclusion:The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia.

外文关键词：

Jianpi Shengxue tabletrenal anemiarandomizedopenparallel controlmulticenter clinical study

作者：

Juan YANG、Meng-yuan LIANG、Yu LI、Hao ZHANG、Wei LI、Jing LV、Li-ping DONG、Jing-song JIN、Cheng YANG、Qing-hong ZHANG、Li LONG、Rong ZOU、Yi GAO、Dan SONG、Chun-qin PAN、Ying YAO、Xiao-lin ZHAN、Xiao-hui WANG

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作者单位：

Department of Nephrology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China

Department of Nephrology,The First People's Hospital of Guiyang,Guiyang 550000,China

Department of Nephrology,The Third Xiangya Hospital,Central South University,Changsha 410000,China

Department of Nephrology,the First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061,China

Department of Nephrology,Wuhan No.4 Hospital,Wuhan 430033,China

Department of Nephrology,Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan 430060,China

Department of Nephrology,Central Theater General Hospital of PLA,Wuhan 430064,China

Department of Nephrology,Taihe Hospital,Shiyan 442000,China

Department of Nephrology,Third People's Hospital of Hubei Province,Wuhan 430033,China

Department of Nephrology,Hubei Province Integrated Traditional Chinese and Western Medicine Hospital of Hubei province,Wuhan 430024,China

Department of Nephrology,Xi'an No.3 Hospital,Affiliated Hospital of Northwest University,Xi'an 710000,China

Department of Nephrology,Shenzhen Guangming District People's Hospital,Shenzhen 518000,China

Department of Nephrology,Xiantao First People's Hospital,Xiantao 433000,China

Department of Nutrition,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China

Department of Nephrology,Huangshi Central Hospital,Huangshi 435000,China

Department of Nephrology,The Fifth Hospital of Wuhan,Wuhan 430050,China

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出版年：

2024

DOI：

10.1007/s11596-024-2867-1

当代医学科学(英文)

华中科技大学同济医学院

当代医学科学(英文)

影响因子：0.748

ISSN：2096-5230

年,卷(期)：2024.44(3)