Diagnosis and Treatment of Extra-articular Tenosynovial Giant Cell Tumor in Soft Tissue:A Report of 33 Cases
Objective To investigate the clinical features,imaging manifestations and prognosis of tenosynovial giant cell tumor(TSGCT)in a rare site in order to improve the understanding of the disease.Methods Thirty-one cases reported in the literature were retrieved,and the data of two patients admitted to our hospital were retrospectively analyzed.Results Among the 33 patients,17 were male and 16 were female,with a mean age of 39.8 years and a mean maximum tumor diameter of 7.2 cm.The tumors were mostly loca-ted in the thigh,buttock,head and neck.The main clinical manifestations were masses(39.4％)and pain with swelling(12.1％).Soft tissue masses of equal or slightly low density were detected through CT examination,and there was no calcification or ossification in the lesion.Mainly low signal or mixed iso-hypo signal in T1WI and mostly mixed signal in T2WI(95.2％)were detected through MRI,and the enhancement was heterogeneous.The risk of recurrence or metastasis was 17.6％in 17 patients who were followed-up.Conclusion Extra-articular TSGCT within soft tissue is very rare.Diagnosis of TSGCT should be considered,if there were soft tissue masses from lower extremities,head and neck.Mixed signals were observed on MRI,and extra-articular sources were observed on CT.Surgical treat-ment can effectively control the progress of TSGCT.
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